Hydrocortisone(hahy-druh-kawr-tuh-zohn) | |
Category | Anti-inflammatory |
Parameter | Effect | Result on hair growth |
DHT | UNKNOWN | |
5a-reductases | UNKNOWN | |
PGD2 | UNKNOWN | |
PGE2 | UNKNOWN | |
PGF2 | UNKNOWN | |
CRTH2 | UNKNOWN |
|
Kirklands version of the 1% cream. | Hydrocortisone Cream |
Description | Hydrocortisone are non anabolic steroids often used as an anti inflammatory to reduce inflammation and suppression of immune system action. One study showed increased skin vasculature after treatment with corticosteroids. |
Typical Results | Some users report moderate regrowth |
Typical Dosages | N/A |
Significant Side Effects | Possible complications from long term use |
Pharmacology Pharmacodynamics | Topical corticosteroids share anti-inflammatory, anti-pruritic and vasoconstrictive actions. The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare and predict potencies and/or clinical efficacies of the topical corticosteroids. There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man. |
Clinical Studies | Abstract |
The blood vessels of the scalp in patients with alopecia areata before and after corticosteroid therapy. | SUMMARY: The blood supply to the hair follicles has been studied by alkaline phosphatase staining in 31 patients with alopecia areata or totalis. Biopsies were taken before, during and after treatment with intralesional or systemic corticosteroids. The restoration of the normal pattern of the skin vasculature accompanies the re-establishment of normal hair growth, whether this is induced by corticosteroids or occurs spontaneously. |